Demineralised Bone Matrix
Demineralised Bone Matrix is a form of bone regeneration which is surgically placed within bone wound sites to fill bone defects, increasing new bone formation and accelerating healing. Demineralised bone is prepared by exposing bone to dilute acid. This gradually dissolves the mineral component of the bone, exposing its protein scaffold.
How it Works
The protein scaffold of bone is comprised primarily of collagen, with a small quantity of non-collagenous proteins. These include a group of powerful growth factors called a bone morphogenetic proteins (BMPs). BMPs are capable of inducing the formation of new bone by influencing the migration and differentiation of stem cells into bone forming cells. These cells subsequently become incorporated into the mineralising matrix of new bone.
- Successful Clinical Bone Regeneration Application
- Osteoconductive and Osteoinductive
- Available in Putty and Paste Variations
Sterility & Safety
Due to the way in which DBM is prepared it is by definition a very safe form of allograft. It undergoes a lengthy processing protocol that includes washing at elevated temperatures and demineralisation. This process depletes any initial contamination and the bioburden present on the graft is assessed before processing begins, and if it is deemed too high then the graft isn not made available for clinical use. After processing all DBM grafts are terminally sterilised with gamma irradiation.
Demineralised Bone Matrix Supplies UK
As a specialist Demineralised Bone Matrix UK Supplier we offer a variety of options for NHS and Private Hopsital Surgeons across the UK to provide effective DBM implants to patients requiring bone regeneration procedures. Our professional team operate across the whole of the UK and are happy to offer further information, advice and provide a product demonstration on any of our demineralised bone matrix supplies.