- Spine: Intertransverse process fusion
- Hand: Cystic scaphoid nonunion
- Foot & Ankle: - Tibial osteotomy - Hindfoot and ankle nonunions
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Accell Connexus is 2nd Generation DBM with a DBM content of close to 70%. It is sold in a syringe form and also contains the unique RPM carrier, giving it exceptional handling characteristics. Accell Connexus can be mixed with any Allograft, Autograft or a synthetic scaffold to provide the ideal recipe for fusion. Accell Technology features a patented process that produces the Accell bone matrix (ABM) which is an open-structured, dispersed form of Dynamic Bone Matrix (DBM). The ABM uses a skeletally mature sheep model with cylindrical 5mm metatarsal defect which is created in tibial diaphysis which shows results after 4 weeks. This benefits from validated osteoinductive potential, is mouldable and easy to pack into defects making it ready to use. Case studies have shown positive results when used in:
Allograft bone is an ideal alternative to autograft for quick, complete bone regeneration. Cancellous chips and granules form the Osteoconductive scaffold for new bone formation while maintaining the porosity essential for tissue and vascular regrowth. Cancellous Bone packs well into any size or shape defect, for maximum surgical flexibility and is available for immediate use with no refrigeration or thawing required. Potential complications of iliac crest bone harvesting, such as morbidity, limited supply, and pain, make Cancellous bone an ideal autograft substitute which has been obtained from an AATB-Accredited Tissue Bank, ensuring the highest quality bone through rigorous donor screening, testing and sterilisation. In many cases, cancellous bone is preferable to cortical bone due to its higher surface area and open porous structure that allows for easy cellular penetration and incorporation and is a perfect compliment to IsoTis’ Accell® product line, and can be used as a bone graft extender or for composite grafting. We supply Allograft Cancellous Bone in a variety of sizes which can be purchased in chip or crushed formation - please see the tab below for further information. We use a guaranteed 24 hour delivery service for this product.
DynaGraft® II is a bone graft substitute composed of demineralized bone matrix (DBM) and a poloxamer Reverse Phase Medium (RPM) which is a biocompatible carrier. The poloxamer (RPM) turns more adhesive whilst at body temperature, providing exceptional handling and containment characteristics for surgeons. The graft is irrigation resistant, moldable, packable and can be mixed with other grafting materials. The cortical bone obtained for the demineralised bone matrix is only supplied from AATB-accredited tissue banks which is then processed into DBM in a state-of-the-art facility. As well as providing a demineralisation process, the demineralised bone matrix also undergoes Electron Beam Sterilisation which is the process of sterilising DBM and ABM under aseptic conditions.We offer a 24 hour delivery service for this product.
Integra Mozaik is a collagen ceramic osteoconductive scaffold which is engineered to mimic the composition and structure of natural bone. Mozaik is made up of 80% purified beta-TCP granules & 20% Highly purified type-1 collagen. The TCP provides bone void filling structure whilst the collagen enables a bioactive element inductive to bone growth, an ideal combination. Mozaik is available in two forms in various sizes: Strips & Putties.
Compression Resistant Strip
- Retains bioactive fluids within scaffold to facilitate protein binding.
- Maintains graft volume under compression.
- Bends to conform to uneven surfaces.
- Excellent handling and moldability.
- Optimal for placement in irregularly shaped defect sites.
Orthoblast II is a powerful choice of bone grafting. It is available in both Putty and Paste form and contains demineralized bone matrix (DBM) to stimulate and regenerate new bone growth. It is a highly inductive material supplied in syringe form (smaller particulate bone granules) and in tub form (larger particulate bone granules). OrthoBlast® II combines demineralized allograft bone with cancellous bone and a reverse phase medium (RPM) to provide an osteoconductive allograft with ideal handling qualities. OrthoBlast II has enjoyed clinical success in a variety of surgical applications including periarticular defects and long-bone defects. An independent study of two DBM allografts, in cases of metaphyseal and periarticular fractures, concluded that the OrthoBlast success rate was over 30% higher than the alternative allograft product. In another independent study of the use of DBM allograft products in ankle/hindfoot fusion, 14% of patients with a glycerolbased allograft developed a nonunion, versus only 8% for the OrthoBlast patients. We offer a 24 hour delivery service for this product.
OsSatura® TCP consists of pure ß-TCP, which is a combination of calcium and phosphate similar to that found in natural bone. Its structure creates a well-defined and interconnected porosity, with an average of 70%, that provides a high level of osteoconductivity. As it resorbs, OsSatura® TCP releases calcium and phosphate ions that support bone ongrowth and ingrowth. Over time, OsSatura®TCP will be completely resorbed and gradually replaced by newly formed bone. While autograft is the accepted standard for bone grafting, it has several serious drawbacks that include extended surgical time, limited availability, variable bone quality, significant blood loss and donor-site morbidity. As a result, use of the composite graft has become more common as an autograft substitute offering the greatest potential for success. Scientific research has identified three key elements that are required for optimal bone regeneration. Whether in autograft or a composite graft, their presence is essential for enabling surgeons to exercise their skills most effectively in promoting new bone growth: Osteogenic, Osteoinductive and Osteoconductive - OsSatura® TCP features all three key elements for optimal bone regeneration. We offer a 24 hour delivery service for this product